Meet us
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Research in our laboratory is focused on a molecular approach to control various pests.
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Insecticide resistance
We use genomic, proteomic, and metabolomic approaches to understand induced responses to xenobiotic exposure and the evolution of the molecular mechanisms of insecticide resistance. A key focus of our work is the investigation of insect microRNAs (miRNAs), short non-coding RNAs comprising 21 to 22 nucleotides in length that play a crucial role in regulating insecticide resistance development and physiological processes in insect species.
More specifically, we work to functionally characterize miRNAs in fall armyworm (FAW) by their depletion using specific antagomirs, bioinformatics target predictions, cell transfection verification, and phenotype rescue experiments. Our research has identified several miRNAs that play significant roles in regulating vital functions in FAW such as resistance and development.
More specifically, we work to functionally characterize miRNAs in fall armyworm (FAW) by their depletion using specific antagomirs, bioinformatics target predictions, cell transfection verification, and phenotype rescue experiments. Our research has identified several miRNAs that play significant roles in regulating vital functions in FAW such as resistance and development.
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Honey bee research
We have been deeply engaged in honey bee research to promote the health of honey bees and develop a control strategy for honey bee pests, focusing primarily on the application of RNA interference (RNAi) technology. RNA interference (RNAi) is a recently discovered mechanism of gene regulation that demonstrates an important function of noncoding RNAs. This system utilizes small double-stranded RNAs as a guide to target mRNAs in a sequence-specific manner and repress the encoded gene. We are studying the RNAi technique to control honey bee pests, notably Varroa destructor.
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Mode of action of Fumigants
We utilize the red flour beetle, Tribolium castaneum, as a model insect to elucidate the mode of action of fumigants such as carbonyl sulfide and phosphine. This research theme can provide valuable information to develop management strategies for the control of stored grain pests using fumigants. Through these multifaceted approaches, our laboratory is dedicated to the understanding and development of molecular-based pest management solutions.
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Lab of Insect Molecular Biology
Department of Applied Biology, College of Agriculture and Life Sciences,
Chungnam National University, Daejeon, Korea
충남대학교 농업생명과학대학 1호관 1426 곤충분자생물학 실험실
Tel: +82 42-821-5763, [email protected]
사이트 관리 담당자: 정희진 ( [email protected])
Department of Applied Biology, College of Agriculture and Life Sciences,
Chungnam National University, Daejeon, Korea
충남대학교 농업생명과학대학 1호관 1426 곤충분자생물학 실험실
Tel: +82 42-821-5763, [email protected]
사이트 관리 담당자: 정희진 ( [email protected])